Lahore: England captain Moeen Ali won the toss and sent Pakistan in to bat in the fifth Twenty20 at Gaddafi stadium in Lahore on Wednesday.
The seven-match series is tied at 2-2 after the first leg of four matches in Karachi with England winning the first and third while Pakistan won the second and fourth.
England made four changes from the side that lost the fourth game, bringing in Chris Woakes for his first game of the series in addition to Dawid Malan, Sam Curran and Mark Wood.
The quartet replaced Will Jacks, Olly Stone, Reece Topley and Liam Dawson.
Pakistan handed a T20I debut to 26-year-old all-rounder Aamer Jamal while also adding Shadab Khan and Haider Ali to the squad. They replaced Khushdil Shah, Usman Qadir and Mohammad Hasnain.
The remaining matches are also in Lahore (September 30 and October 2).
Pakistan: Babar Azam (captain), Mohammad Rizwan, Asif Ali, Aamer Jamal, Haris Rauf, Iftikhar Ahmed, Shadab Khan, Mohammad Nawaz, Haider Ali, Shan Masood, Mohammad Wasim Junior
England: Moeen Ali (captain), Dawid Malan, Harry Brook, Sam Curran, Ben Duckett, Chris Woakes, Alex Hales, Adil Rashid, Phil Salt, Mark Wood, David Willey
Umpires: Aleem Dar (PAK) and Ahsan Raza (PAK)
TV umpire: Asif Yaqoob (PAK)
Match referee: Javed Malik (PAK)